Clinical Stage Pharma

Developing small molecules for the treatment of gastric acid related diseases.

About Cinclus Pharma
Cinclus Pharma

The Next Leap Forward

Blockbuster Proton Pump Inhibitors (PPIs) such as Losec and Nexium have not been able to provide all gastroesophageal reflux disease (GERD) patients with sufficient disease control. Time has now come for Potassium-Competitive Acid Blockers (P-CABs) to take the next leap forward in the treatment of acid related diseases. Cinclus Pharma’s clinical stage drug candidate linaprazan glurate, formerly known as X842, takes a new approach to provide improved management of GERD.

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Latest pressreleases

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Our lead asset

Linaprazan glurate

Built on world-leading industrial tradition, Linaprazan glurate is a gastric acid blocker and therapy with great potential for healing GERD. During 2021, clinical phase 1 trials were successfully completed and clinical phase II trials were initiated. Linaprazan glurate represents a new and novel mode of action with superior efficacy and pharmacokinetic profile versus PPI’s.

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Latest News

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Peter Unge – Clinician and senior advisor with extensive experience in gastroenterology

Peter Unge's knowledge and long experience are essential assets in the clinical operations of Cinclus Pharma.

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Cinclus Pharma at the ABGSC – Life Science Summit

Cinclus Pharma participated in the ABGSC Life Science Summit, where CEO Christer Ahlberg presented the recent company updates and the development of linaprazan glurate.

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Maria Engström – Ambitious CFO with a passion for development

Maria Engström, CFO at Cinclus Pharma, shares her perspective on driving change and supporting company growth and development.

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Reflux diseases


Most people can relate to discomfort caused by reflux and heartburn, two of the most common symptoms caused by GERD. Symptoms often occur during or after eating and drinking, which affects both motivation and the ability to enjoy social activities such as picnics, dinners, events or just a cup of coffee with friends. More severe stages of GERD can be very painful, with difficulty in swallowing and esophageal erosions or ulcerations (esophagitis).

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“We want to make a paradigm shift in the treatment of gastric acid related diseases. We will do this by registering, launching, and making our effective P-CAB linaprazan glurate available worldwide.”

Christer Ahlberg

CEO Cinclus Pharma