Addressing an unmet medical need in GERD
Highlights from the 2024 Annual Report: Market overview
Significant proportion of severe eGERD patients treated by Gastroenterologists remain unhealed with PPI treatment.
GERD remains a major challenge and medical need worldwide. The more severe degrees of eGERD, grades C and D on the Los Angeles scale, are diagnosed in a total of nineteen million people worldwide. About ten million of these are located in the U.S. and Europe. According to gastroenterologists feedback more than a third of USA patients are not helped and in Europe the figure is as high as 43%.
There is a large proportion of unhealed patients in all grades, from A to D. In clinical trials, more than 30% of patients with eGERD grade C and more than 50% of those suffering from grade D remain unhealed after treatment with PPIs 3). A significant proportion of eGERD patients suffer from nocturnal symptoms. 1,2)
